Spine

Reduce adhesion formation following spine surgery

Even with the best surgical technique, postoperative adhesions can form, creating pressure on nerves and local irritation. This can lead to pain, neurological deficits and other long-term complications, including Failed Back Surgery Syndrome (FBSS). Fziomed’s Adhesion Barrier Gel products are the leading choice of spine surgeons worldwide, backed up by more than two decades of clinical experience improving patient outcomes and preserving surgical excellence.

Formulated specifically for spine surgery, Oxiplex® (also sold under the brand names Interpose®, MediShield™ and Oxiplex/SP® Gel) provides a temporary, protective separation of tissues adjacent to the site of the surgery during the body’s natural healing process, reducing the formation of adhesions that can cause postoperative pain and other complications.

More than 750,000 spine patients treated since 2002

Product Overview Reduce Pain, Improve Outcomes Proven Safety and Efficacy Ease of Use Patient Satisfaction Stability

Product Overview

Oxiplex is intended to be placed around neural tissues following spine surgery to reduce adhesion formation and related symptoms such as pain.

Oxiplex gel is supplied sterile, ready to use in a 3mL syringe with a flexible applicator.

Oxiplex gel is designed for use in spine surgeries. The absorbable gel coats and isolates neural elements and dura, serving as a protective physical barrier that can reduce the formation of epidural fibrosis (adhesions) and can limit the exposure of nerves to biochemical irritants produced during surgery that may cause pain.

Reduce Pain, Improve Outcomes

Oxiplex has been shown to significantly reduce pain following spinal surgery.^1,2,3, It works in concert with the body’s natural healing process to reduce adhesion formation. This can lead to higher patient satisfaction and may help reduce the risk of long-term complications, including Failed Back Surgery Syndrome (FBSS).

Patients experiencing severe leg and back pain at baseline that were treated with Oxiplex saw significantly greater improvement in pain scores at 6 months.¹

Proven Safety and Efficacy

With over 20 years of clinical use, Oxiplex has been proven safe and effective in more than 750,000 spinal procedures worldwide, supported by numerous published clinical studies. Our patented dual-polymer formulation contains no pharmaceutical agents or materials of human, animal, or bacterial origin.

Ease of Use

Oxiplex is provided sterile, ready to use, and requires no mixing or special handling or storage conditions. The prepackaged, flexible applicator allows for easy application, while the clear absorbable gel maintains operative site visibility.

Patient Satisfaction

Reducing postoperative pain and adhesiogenic complications can lead to improved patient satisfaction and outcomes, minimizing potential risks in future operations and patient complaints.

Oxiplex treated patients experienced fewer reoperations within the 3-months of the initial operation an occurred at the same level.¹

Stability

Oxiplex gel’s unique viscosity is flowable yet remains where applied with no change in volume that could adversely affect nearby tissue or nerves.

Download the Oxiplex instructions for use

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References

Rhyne A, et al. Oxiplex reduces leg pain, back pain and associated symptoms following lumbar discectomy. Spine. 2012;37:631-41.
Fransen P. Safety of carboxymethylcellulose / polyethylene oxide for the prevention of adhesions in lumbar disc herniation, consecutive case series review. Annals of Surg Inn Res. 2008.
Assietti R, et al. Use of carboxymethylcellulose/polyethylene oxide gel in microdiscectomy with interlaminectomy, a case series comparison with long-term follow-up. Spine. 2008.

Fziomed, Inc.
231 Bonetti Drive
San Luis Obispo, CA 93401
USA
Phone: +1 (805) 546-0610
Fax: +1 (805) 546-0571
Email: [email protected]

Fziomed products are not currently available in the United States.

The following trademarks are owned by Fziomed, Inc. and registered in the United States and certain foreign jurisdictions: FZIOMED®, OXIPLEX®, OXIPLEX/SP®, DYNAVISC®, INTERPOSE®, INTERCOAT®, OXIPLEX/AP®, and OXIPLEX/IU®.

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