Intercoat IU Adhesion Barrier Gel for intrauterine use (also sold under the brand name Oxiplex/IU®) provides a temporary, protective separation of tissues during the body’s natural healing process, reducing adhesion formation.

Preserve surgical excellence – Improve patient outcomes

Product Overview

Intercoat IU is intended for use as an adjunct to intrauterine procedures for reducing the incidence, extent, and severity of adhesions.

Intercoat IU gel is supplied sterile, ready to use in a 10mL syringe with an applicator designed specifically for intrauterine use.

Reduced Infertility Risk and Improved Outcomes

A randomized clinical study showed that patients treated with Intercoat IU Adhesion Barrier Gel demonstrated fewer de novo adhesions and improved patency of the Fallopian tube and uterine ostia.1 A second clinical study showed patients treated with Intercoat IU Adhesion Barrier Gel had fewer moderate to severe adhesions and an improved fertility rate.2

Safety and Efficacy

Our patented dual-polymer formulation combines two biocompatible synthetic polymers proven safe and effective over more than two decades of worldwide use. Intercoat IU Adhesion Barrier Gel is absorbable, and contains no pharmaceutical agents or materials of human, animal, or bacterial origin.

Ease of Use

Intercoat IU is provided sterile, ready to use, and requires no mixing or special handling or storage conditions. The prepackaged, smooth, rounded tip applicator allows for safe insertion and ease of application while the clear absorbable gel maintains local visibility.

Patient Satisfaction

Reducing postoperative pain and adhesiogenic complications can lead to improved reproductive health and patient satisfaction, minimizing potential risks in future operations and patient complaints.

Stability

Intercoat IU gel’s unique viscosity is flowable yet remains where applied with no change in volume that could adversely affect nearby tissues.

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References

  1. Di Spiezio, Sardo, et al. Efficacy of a polyethylene oxide-sodium carboxymethylcellulose gel in prevention of uterine adhesions after hysteroscopic surgery. JMIG. 2011(Apr);18(4):462-9.
  2. Fuchs N, Smorgick N, et al. Intercoat (Oxiplex/AP Gel) for preventing intrauterine adhesions after operative hysteroscopy for suspected retained products of conception: double-blind, prospective, randomized pilot study. JMIG. 2013(July);21(1):126-130.

Last update: Feb. 25, 2025